😉😌😌😄😄😃😃🙏🙏🙏🙏🙏🙏🙏🙏🙏“If I take the wings of the morning, And dwell in the uttermost parts of the sea; Even there shall thy hand lead me, And thy right hand shall hold me. If I say, Surely the darkness shall cover me; Even the night shall be light about me. Yea, the darkness hideth not from thee; But the night shineth as the day: The darkness and the light are both alike to thee.” Psalm 139:9-12 KJV https://bible.com/bible/1/psa.139.9-12.KJV“My substance was not hid from thee, When I was made in secret, and curiously wrought in the lowest parts of the earth. Thine eyes did see my substance, yet being unperfect; And in thy book all my members were written, Which in continuance were fashioned, When as yet there was none of them. How precious also are thy thoughts unto me, O God! How great is the sum of them! If I should count them, they are more in number than the sand: When I awake, I am still with thee.” Psalm 139:15-18 KJV https://bible.com/bible/1/psa.139.15-18.KJV“Search me, O God, and know my heart: Try me, and know my thoughts: And see if there be any wicked way in me, And lead me in the way everlasting.” Psalm 139:23-24 KJV https://bible.com/bible/1/psa.139.23-24.KJV
Cannabis molecules, specifically cannabinoids like THC (tetrahydrocannabinol) and CBD (cannabidiol), are known to accumulate in the body’s fatty tissues over time due to their high lipophilicity (fat solubility). Because these compounds are stored in fat rather than being immediately excreted, they can build up, particularly in chronic users, and remain detectable in the system for days or weeks.
Kidney become………
Mechanisms of Buildup (Pharmacokinetics)
Storage in Adipose Tissue: THC and CBD are rapidly taken up by fat tissue, organs, and the brain.
Slow Release: As fat stores are metabolized, stored THC is slowly released back into the bloodstream, leading to extended detection times.
Metabolism: The liver breaks down THC into metabolites, specifically 11-OH-THC and 11-COOH-THC.
Half-Life: The plasma half-life of THC ranges from 1–3 days for occasional users to 5–13 days for chronic users. National Institutes of Health (.gov) +1
2. Effects of Accumulation
Tolerance: Chronic exposure to high levels of cannabinoids can lead to a decrease in CB1 receptor density (downregulation), which makes the endocannabinoid system less sensitive and results in higher tolerance.
Cannabinoid Hyperemesis Syndrome (CHS): Heavy, long-term use can lead to CHS, a condition characterized by severe stomach pain and cyclical vomiting.
Reversibility: Studies suggest that receptor downregulation is reversible, with sensitivity returning after roughly 4 weeks of abstinence. National Institutes of Health (.gov) +1
3. Molecular Action
Binding to Receptors: THC mimics natural endocannabinoids (like anandamide) by binding to CB1 receptors in the brain, which controls neural signaling.
Fat Conversion: CBD has been shown in studies to stimulate genes that break down fat and convert “white fat” (which stores energy) into “brown fat” (which burns energy). Wu Tsai Neurosciences Institute +4
4. Detection Times
Because of this buildup, drug tests can detect metabolites weeks after consumption:
Occasional User: 1–3 days.
Moderate User: 4–7 days.
Chronic User: 10–30+ days (depending on metabolism and fat
Heal YourBody, Please!🙏
“For I am now ready to be offered, and the time of my departure is at hand. I have fought a good fight, I have finished my course, I have kept the faith: henceforth there is laid up for me a crown of righteousness, which the Lord, the righteous judge, shall give me at that day: and not to me only, but unto all them also that love his appearing.” 2 Timothy 4:6-8 KJV https://bible.com/bible/1/2ti.4.6-8.KJV
Research suggests that while cannabis is not heavily linked to liver failure in general populations, long-term, heavy use of THC (tetrahydrocannabinol) can lead to liver strain, fat buildup (steatosis), and inflammation. The symptoms you are describing—side pain (upper right abdomen)—are often associated with liver stress or Cannabinoid Hyperemesis Syndrome (CHS), a condition caused by chronic cannabis use.
Why Is This Easy For Us To Do…….
The Chemical: THC and its Metabolites
THC & 11-Hydroxy-THC: When THC is ingested (especially in edibles), it is processed by the liver (first-pass metabolism) and converted into a potent metabolite called 11-hydroxy-THC. This metabolite can cause significant strain on liver enzymes (CYP450 system).
CB1 Receptors: THC activates CB1 receptors in the liver. Overactivation of these receptors can cause fat accumulation (steatosis), inflammation, and the progression of liver fibrosis. Premiere Addiction Recovery +4
2. The Buildup and Liver Pain
Liver Stress/Inflammation: Heavy THC use can increase liver enzymes (ALT/AST), which are indicators of liver strain.
Fat Accumulation (Steatosis): Regular use can trigger “fatty liver” in some individuals, particularly if they have underlying conditions, leading to pain or swelling in the upper right abdomen.
Cannabinoid Hyperemesis Syndrome (CHS): Chronic users may develop CHS, characterized by severe nausea, vomiting, and intense abdominal (side) pain. This pain is often accompanied by “abdominal discomfort in the upper right side” where the liver is located. Cedars-Sinai +3
3. Factors Worsening Liver Strain
Edibles: Because edibles undergo extensive first-pass metabolism, they put more direct work on the liver than smoking or vaping.
Mixing Substances: Combining THC with alcohol or medications (such as acetaminophen) significantly increases the risk of damage.
Pre-existing Conditions: People with fatty liver disease or hepatitis are more vulnerable to THC-induced liver injury. Premiere Addiction Recovery +3
When to see a doctor: If you are experiencing pain in the upper right abdomen, persistent fatigue, or yellowing of the skin/eyes (jaundice), these are warning signs of liver stress. Premiere Addiction Recovery
Disclaimer: This information is for educational purposes based on research and does not constitute medical advice. Always consult a healthcare professional regarding pain or liver concerns.
Hello!!
“I charge thee therefore before God, and the Lord Jesus Christ, who shall judge the quick and the dead at his appearing and his kingdom; preach the word; be instant in season, out of season; reprove, rebuke, exhort with all longsuffering and doctrine. For the time will come when they will not endure sound doctrine; but after their own lusts shall they heap to themselves teachers, having itching ears; and they shall turn away their ears from the truth, and shall be turned unto fables. But watch thou in all things, endure afflictions, do the work of an evangelist, make full proof of thy ministry.” 2 Timothy 4:1-5 KJV https://bible.com/bible/1/2ti.4.1-5.KJV
“And while they abode in Galilee, Jesus said unto them, The Son of man shall be betrayed into the hands of men: and they shall kill him, and the third day he shall be raised again. And they were exceeding sorry. And when they were come to Capernaum, they that received tribute money came to Peter, and said, Doth not your master pay tribute? He saith, Yes. And when he was come into the house, Jesus prevented him, saying, What thinkest thou, Simon? of whom do the kings of the earth take custom or tribute? of their own children, or of strangers? Peter saith unto him, Of strangers. Jesus saith unto him, Then are the children free. Notwithstanding, lest we should offend them, go thou to the sea, and cast an hook, and take up the fish that first cometh up; and when thou hast opened his mouth, thou shalt find a piece of money: that take, and give unto them for me and thee.” Matthew 17:22-27 KJV https://bible.com/bible/1/mat.17.22-27.KJV
“And it came to pass, that, while Apollos was at Corinth, Paul having passed through the upper coasts came to Ephesus: and finding certain disciples, he said unto them, Have ye received the Holy Ghost since ye believed? And they said unto him, We have not so much as heard whether there be any Holy Ghost. And he said unto them, Unto what then were ye baptized? And they said, Unto John’s baptism. Then said Paul, John verily baptized with the baptism of repentance, saying unto the people, that they should believe on him which should come after him, that is, on Christ Jesus. When they heard this, they were baptized in the name of the Lord Jesus.” Acts 19:1-5 KJV https://bible.com/bible/1/act.19.1-5.KJV
“Then said he unto the disciples, It is impossible but that offences will come: but woe unto him, through whom they come! It were better for him that a millstone were hanged about his neck, and he cast into the sea, than that he should offend one of these little ones.” Luke 17:1-2 KJV https://bible.com/bible/1/luk.17.1-2.KJV
Hi 😀😃😄😄😁😆😆🖐️🖐️🖐️🧠🧠🧠🧠🧠🧠😄😄😄🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀🫀
“How precious also are thy thoughts unto me, O God! How great is the sum of them! If I should count them, they are more in number than the sand: When I awake, I am still with thee. Surely thou wilt slay the wicked, O God: Depart from me therefore, ye bloody men. For they speak against thee wickedly, And thine enemies take thy name in vain. Do not I hate them, O LORD, that hate thee? And am not I grieved with those that rise up against thee? I hate them with perfect hatred: I count them mine enemies. Search me, O God, and know my heart: Try me, and know my thoughts: And see if there be any wicked way in me, And lead me in the way everlasting.” Psalm 139:17-24 KJV https://bible.com/bible/1/psa.139.17-24.KJV
National Institutes of Health (.gov) +1
Wu Tsai Neurosciences Institute +4
Premiere Addiction Recovery +4
Cedars-Sinai +3
